The Axiom Equine Genotyping Array (Axiom MNEC670) for equine genotyping was designed through Affymetrix’s Expert Design Program in collaboration with the University of Minnesota and members of the Equine Genetic Diversity Consortium.

The Axiom Equine Genotyping Array is a novel array and the only one that can be used to genotype 20 different breeds. It offers maximum utility for equine genetics research. It features 670,796 markers that were selected from a pool of 2 million markers for optimal genomic coverage of known genetic diversity among domestic horse breeds. Developed by Axiom Genotyping Solution, the array offers the highest data completeness, call rates, and reproducibility of any technology currently available.

Features of Axiom® Equine Genotyping Array:

• Expert design: developed by key opinion leaders in the equine community
• High resolution: available in 96-well format; compatible with a wide range of genotyping applications for equine research.

Featured content:

• Axiom Equine Genotyping Array includes a total of 670,796 markers:
  • Approximately 400,000 markers among population tag SNPs
  • Approximately 200,000 markers within population tag SNPs
  • Approximately 70,000 SNPs from inherited arrays
  • Additional SNP density within the equine major histocompatibility complex

Diversity:

Axiom Equine Genotyping Array includes markers that were selected to maximize imputation accuracy up to 1.8 million markers both within and across 20 breeds (Fig. 1). Emphasis was placed on breeds of high commercial relevance.

Applications of Axiom Equine Genotyping Array:

• Complex trait research
  
  • Genome-wide analysis and fine mapping
  • Diversity analysis
  • Genomic prediction of disease risk

• Molecular breeding
  
  • Association mapping
  • Improving breeding program efficiency
  • Selection signature analysis

* The Equine Genetic Diversity Consortium (EGDC) led by the University of Minnesota represents a collaborative international community of equine researchers who are working to build a comprehensive understanding of genetic diversity among equine populations worldwide. (http://www.cvm.umn.edu/equinegenetics/egdc/)